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Outsourced sterile compounding is often a strategic decision for advancing patient safety and creating operational efficiency—especially in the perioperative/operating room (O. As an FDA registered 503B outsourcing facility, Phar MEDium endeavors to provide the broadest portfolio of compounded sterile preparations (CSPs) and ready to use prefilled O. ” American Society of Health-System Pharmacists Summary Meeting and Exhibition.
Amer Soc of Anesthesiologists Meeting, Chicago, IL, 2011. Chernin E, “Medication Safety in the Operating Room – What’s Different?
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefazolin for Injection, USP and other antibacterial drugs, Cefazolin for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.
When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy.
If leaks are detected, discard solution as sterility may be impaired. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
As with other cephalosporins, cefazolin tends to darken depending on storage conditions; within the stated recommendations, however, product potency is not adversely affected. Product containers may be fragile in the frozen state. BEFORE THERAPY WITH ANCEF IS INSTITUTED, CAREFUL INQUIRY SHOULD BE MADE TO DETERMINE WHETHER THE PATIENT HAS HAD PREVIOUS HYPERSENSITIVITY REACTIONS TO CEFAZOLIN, CEPHALOSPORINS, PENICILLINS, OR OTHER DRUGS.
Presented at American Society of Anesthesiologists Meeting.
The perioperative use of Cefazolin for Injection may also be effective in surgical patients in whom infection at the operative site would present a serious risk (e.g., during open-heart surgery and prosthetic arthroplasty).General Product Information: Cefazolin is an injectable antibiotic from the cephalosporin family of antibiotics.It is used to treat infections including bacterial infections and is used in some surgical procedures.…Cefazolin for Injection is effective in the eradication of streptococci from the nasopharynx; however, data establishing the efficacy of Cefazolin for Injection in the subsequent prevention of rheumatic fever are not available at present.Urinary tract infections due to (penicillin-sensitive and penicillin-resistant) and group A beta-hemolytic streptococci.